Name | 4-Phenylsemicarbazide |
Synonyms | AKOS B001501 Phenylsemicarbazide 1-Amino-3-phenylurea 4-PHENYLSEMICARBAZIDE 4-Phenylsemicarbazide LABOTEST-BB LT02089391 Anilinoformylhydrazine Semicarbazide, 4-phenyl- |
CAS | 537-47-3 |
EINECS | 208-669-2 |
InChI | InChI=1/C7H9N3O/c8-10-7(11)9-6-4-2-1-3-5-6/h1-5H,8H2,(H2,9,10,11) |
Molecular Formula | C7H9N3O |
Molar Mass | 151.17 |
Density | 1.2100 (rough estimate) |
Melting Point | 122-125°C(lit.) |
Boling Point | 273.17°C (rough estimate) |
Water Solubility | 699.5mg/L(15 ºC) |
Merck | 14,7312 |
BRN | 511107 |
pKa | 10.52±0.20(Predicted) |
Storage Condition | Keep in dark place,Inert atmosphere,Room temperature |
Sensitive | Air Sensitive |
Refractive Index | 1.5860 (estimate) |
MDL | MFCD00007590 |
Physical and Chemical Properties | White flake or needle-like crystals. Melting point 128 ℃. Easily soluble in alcohol, chloroform, dilute acid and alkali, hardly soluble in hot water, insoluble in ether. Its hydrochloride is prismatic crystal with a melting point of 215 ℃. |
Hazard Symbols | Xi - Irritant |
Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin. |
Safety Description | S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. |
WGK Germany | 3 |
FLUKA BRAND F CODES | 8-10-23 |
Hazard Class | IRRITANT |
chemical properties | white flaky or needle-like crystals. Melting point 128 ℃. Easily soluble in alcohol, chloroform, dilute acid and alkali, hardly soluble in hot water, insoluble in ether. Its hydrochloride is prismatic crystal with a melting point of 215 ℃. |
use | this product is a reagent for the determination of ketones and aldehydes. |
production method | 68g of phenylurea and 120ml of 42% hydrazine hydrate are heated for 12h, and the activated carbon of the reaction mixture is decolorized and concentrated, cooled and crystallized to obtain 47-52g of crude product. Dissolve the crude product in absolute ethanol and use concentrated hydrochloric acid to form a salt to obtain 46-48g of 4-phenylsemicarbazide hydrochloride. Dissolve hydrochloride in boiling water, add sodium hydroxide solution, precipitate free alkali, filter and dry to obtain 28-30g4-phenylsemicarbazide. |